NHS chief executive Sir Simon Stevens said he hoped the public would use the anniversary as an opportunity to “say a heartfelt thank you” to hospital staff.
Sir Simon said: “This year has been the most challenging in NHS history, with staff displaying extraordinary dedication, skill and compassion to care for the 100,000 patients with Covid-19 who needed specialist hospital treatment and many others besides.
“During this testing time our nurses, doctors, physios, pharmacists and countless more colleagues were sustained by the support of the public, not least through the weekly applause for key workers.
“No health service, not even the NHS, could have coped alone with this coronavirus pandemic.”
Chief executive for NHS Wales, Dr Andrew Goodall, said Clap for Carers was “very much embraced” in Wales, and he was “delighted” to support it.