Weight regain after obesity drugs tied to higher odds of suicidal thoughts in observational study
More research is needed to determine whether weight-loss medications themselves affect mental health, or whether depression and other symptoms are related to factors such as obesity or difficulties losing weight.
The researchers also need to determine whether mental health risks differ between specific weight-loss drugs.
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“Even though GLP-1 clinical trials show low absolute risk, the FDA’s product labels for chronic weight management drugs (like Wegovy and Zepbound) include warnings to monitor for mood changes,” Mitchell noted.
She recommends that a physician conducts a baseline mental health history before prescribing new weight-loss medications, evaluating past or current depression, bipolar disorder, or history of suicidal ideation or behavior.
More research is needed to determine whether weight-loss medications themselves affect mental health, or whether depression and other symptoms are related to factors such as obesity or difficulties losing weight. (iStock)
“Individuals with severe obesity have higher baseline rates of depression, anxiety and body dysmorphia.”
Article source: https://www.foxnews.com/health/weight-regain-obesity-drugs-tied-higher-odds-suicidal-thoughts-observational-study